As the use of Artificial Intelligence (AI) in parliamentary processes becomes increasingly prevalent, it is necessary to establish ethical and operational guidelines that ensure accountability, transparency, and human autonomy, while promoting sustainable development goals and protecting privacy, security, and diversity. With this aim, a technical working group convened on the occasion of the ‘LegisTech: the Americas’ conference in Brasília (13-14 April 2023) to develop a first set of guidelines setting out the ethical and operational principles for the introduction and use of AI in the parliamentary workspace. Central to these guidelines is the understanding that any AI product or process must serve as an instrument to promote and uphold the rights enshrined in the Universal Declaration of Human Rights. These preliminary guidelines are classified into several sections and offer general guidance for parliaments to gradually develop their own custom regulatory framework.